Srila Prabhupada's mission to spread the wisdom of Krishna Consciousness initially faced resistance in India. However, in 1965, at the age of 69, as per the directions of his Guru Srila Bhaktisiddhanta Saraswati Thakura, he ventured to the United States and laid the foundation for the International Society for Krishna Consciousness (ISKCON). Over the ensuing 11 years, he embarked on an extraordinary journey, circumnavigating the globe 14 times. During this period, he inspired his devoted followers, delivered enlightening discourses, and shared the profound philosophy of Krishna Consciousness with eager learners.

Srila Prabhupada's arrival in the United States coincided with a tumultuous period, marked by widespread dissatisfaction with America's involvement in the Vietnam War. The youth of America sought an alternative to the prevailing norms and thus the counterculture movement, commonly known as the "hippie culture," emerged. Srila Prabhupada presented a compelling alternative.

He introduced the Hare Krishna Movement to the public through various means, such as chanting in parks, distributing the Back to Godhead Magazine, organizing love feasts, and delivering lectures on the Bhagavad-gita and Srimad Bhagavatam in rented storefronts. These efforts attracted numerous young individuals who eventually became his disciples.

Srila Prabhupada diligently trained his disciples in the art of Deity Worship, a practice in which the Supreme Lord manifests in the form of Deities to allow devotees to serve Him. By serving the Deities with utmost devotion, the devotees aim to transcend their material attachments and cultivate pure love for God, ultimately leading to a successful and spiritually enriched life.

In a bid to revive the Krishna Conscious tradition, Srila Prabhupada envisioned self-sufficient farm communities rooted in the principles of "Simple Living, High Thinking." In 1972, he established a Gurukul in Dallas, Texas, following the traditional Vedic educational model. He founded 108 Krishna temples and many farm communities. He also gave an ultimatum that no one within a 10-mile radius of an ISKCON temple should go hungry, which eventually led to the birth of The Akshaya Patra Foundation in the year 2000.